ABCB6 RNA expression in leukemias--expression is low in acute promyelocytic leukemia and FLT3-ITD-positive acute myeloid leukemia

Ann Hematol. 2014 Mar;93(3):509-12. doi: 10.1007/s00277-013-1821-2. Epub 2013 Jun 22.
No abstract available

Publication types

  • Comparative Study
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • ATP-Binding Cassette Transporters / blood
  • ATP-Binding Cassette Transporters / genetics
  • ATP-Binding Cassette Transporters / metabolism*
  • Adolescent
  • Adult
  • Aged
  • Antineoplastic Agents / pharmacology
  • Biomarkers, Tumor / blood
  • Biomarkers, Tumor / genetics
  • Biomarkers, Tumor / metabolism*
  • Bone Marrow / metabolism
  • Cell Line, Tumor
  • Child
  • Drug Resistance, Neoplasm
  • Gene Expression Regulation, Neoplastic*
  • Humans
  • Leukemia, Myeloid, Acute / blood
  • Leukemia, Myeloid, Acute / drug therapy
  • Leukemia, Myeloid, Acute / genetics
  • Leukemia, Myeloid, Acute / metabolism*
  • Leukemia, Promyelocytic, Acute / blood
  • Leukemia, Promyelocytic, Acute / drug therapy
  • Leukemia, Promyelocytic, Acute / genetics
  • Leukemia, Promyelocytic, Acute / metabolism*
  • Mutation
  • Neoplasm Proteins / blood
  • Neoplasm Proteins / genetics
  • Neoplasm Proteins / metabolism
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / blood
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / metabolism
  • RNA, Neoplasm / blood
  • RNA, Neoplasm / metabolism*
  • Reactive Oxygen Species / metabolism
  • Tandem Repeat Sequences
  • fms-Like Tyrosine Kinase 3 / blood
  • fms-Like Tyrosine Kinase 3 / genetics
  • fms-Like Tyrosine Kinase 3 / metabolism*

Substances

  • ABCB6 protein, human
  • ATP-Binding Cassette Transporters
  • Antineoplastic Agents
  • Biomarkers, Tumor
  • Neoplasm Proteins
  • RNA, Neoplasm
  • Reactive Oxygen Species
  • FLT3 protein, human
  • fms-Like Tyrosine Kinase 3