Convergent chemical synthesis of histone H2B protein for the site-specific ubiquitination at Lys34

Angew Chem Int Ed Engl. 2013 Jul 29;52(31):8059-63. doi: 10.1002/anie.201303844. Epub 2013 Jun 21.

Authors

Peter Siman¹, Subramanian Vedhanarayanan Karthikeyan, Miroslav Nikolov, Wolfgang Fischle, Ashraf Brik

Affiliation

¹ Department of Chemistry, Ben Gurion University of the Negev, Beer Sheva 84105, Israel.

PMID: 23794525
DOI: 10.1002/anie.201303844

No abstract available

Keywords: H2B protein; chromatin; peptide ligation; proteins; ubiquitination.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Sequence
Chromatin / metabolism
Histones / chemical synthesis
Histones / chemistry*
Lysine / chemistry*
Molecular Sequence Data
Peptides / chemical synthesis
Peptides / chemistry
Protein Processing, Post-Translational
Ubiquitin / chemistry
Ubiquitin / metabolism
Ubiquitination

Substances

Chromatin
Histones
Peptides
Ubiquitin
Lysine