Noninvasive brain stimulation: from physiology to network dynamics and back

Nat Neurosci. 2013 Jul;16(7):838-44. doi: 10.1038/nn.3422. Epub 2013 Jun 25.


Noninvasive brain stimulation techniques have been widely used for studying the physiology of the CNS, identifying the functional role of specific brain structures and, more recently, exploring large-scale network dynamics. Here we review key findings that contribute to our understanding of the mechanisms underlying the physiological and behavioral effects of these techniques. We highlight recent innovations using noninvasive stimulation to investigate global brain network dynamics and organization. New combinations of these techniques, in conjunction with neuroimaging, will further advance the utility of their application.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, N.I.H., Intramural
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Animals
  • Brain / anatomy & histology
  • Brain / physiology*
  • Brain Mapping*
  • Humans
  • Individuality
  • Models, Neurological
  • Neural Pathways / physiology*
  • Nonlinear Dynamics*
  • Transcranial Magnetic Stimulation