Oleaceran: a novel spiro[isobenzofuran-1,2'-naptho[1,8-bc]furan] isolated from a terrestrial Streptomyces sp

Ritesh Raju; Oleksandr Gromyko; Viktor Fedorenko; Andriy Luzhetskyy; Rolf Müller

doi:10.1021/ol401490u

Oleaceran: a novel spiro[isobenzofuran-1,2'-naptho[1,8-bc]furan] isolated from a terrestrial Streptomyces sp

Org Lett. 2013 Jul 19;15(14):3487-9. doi: 10.1021/ol401490u. Epub 2013 Jun 26.

Authors

Ritesh Raju¹, Oleksandr Gromyko, Viktor Fedorenko, Andriy Luzhetskyy, Rolf Müller

Affiliation

¹ Department of Microbial Natural Products, Helmholtz-Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Pharmaceutical Biotechnology, Saarland University, Campus C2 3, 66123 Saarbrücken, Germany.

PMID: 23802119
DOI: 10.1021/ol401490u

Abstract

Chemical analysis of a terrestrial-derived Streptomyces sp. Lv20-195 cultivated from the root zone of Olea europea yielded oleaceran, 1, possessing a novel spiro[isobenzofuran-1,2'-naptho[1,8-b,c]furan] carbon skeleton. The structure of 1 was determined by detailed spectroscopic analysis.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Benzofurans / analysis*
Benzofurans / chemistry*
Benzofurans / isolation & purification
Magnetic Resonance Spectroscopy
Molecular Structure
Spiro Compounds / analysis
Spiro Compounds / chemistry*
Spiro Compounds / isolation & purification
Streptomyces / chemistry*

Substances

Benzofurans
Spiro Compounds
spiro(isobenzofuran-1,2'-naptho(1,8-bc)furan)