Cheek metastasis from a bladder tumor: unusual presentation of an aggressive disease

Urologia. 2013 Sep-Dec;80(4):317-21. doi: 10.5301/urologia.5000022. Epub 2013 Jun 24.

Abstract

Transitional cell carcinoma (TCC) has been well described for its propensity to metastasize to distant sites. Metastases to the soft tissues of the oral cavity from a bladder cancer are extremely rare. We present the case of a 65-year-old man who presented with history of hematuria for 1 month and was found to have high-grade TCC of the bladder. He developed a cheek lesion after 3 weeks, which was diagnosed as metastatic nodule along with pulmonary metastases from high-grade bladder TCC. The patient received chemotherapy followed by the radiotherapy of the cheek lesion, but he succumbed after 3 months due widespread metastatic disease. We also presented a review of the literature regarding this rare presentation.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Carcinoma, Transitional Cell / diagnosis
  • Carcinoma, Transitional Cell / secondary*
  • Cheek / pathology*
  • Facial Neoplasms / diagnosis
  • Facial Neoplasms / secondary*
  • Fatal Outcome
  • Hematuria / etiology
  • Humans
  • Lower Urinary Tract Symptoms / etiology
  • Lung Neoplasms / secondary
  • Lymphatic Metastasis
  • Male
  • Neoplasm Invasiveness
  • Urinary Bladder Neoplasms / complications
  • Urinary Bladder Neoplasms / pathology*