Analysis of surgical and medical management of glaucoma in Sturge-Weber syndrome

Ophthalmology. 1990 Jul;97(7):904-9. doi: 10.1016/s0161-6420(90)32483-1.

Abstract

Management of glaucoma associated with Sturge-Weber syndrome (SWS) is difficult. The authors reviewed 36 eyes of 30 SWS patients with either early or late-onset glaucoma with a mean follow-up of 122 months (range, 24-253 months). Intervals between required surgical or medical interventions were analyzed. Intervention was attributed to elevated intraocular pressure (IOP) in 55% of cases and disc change in 45%. Median stable postoperative interval with goniotomy was 12 months; with trabeculotomy, 21 months; with trabeculectomy, 34 months; with argon laser trabeculoplasty, 25 months; and with medications, 57 months. Survival analysis shows statistically significant differences between goniotomy and medications. Intraoperative choroidal expansions developed in 24% of cases receiving a trabeculectomy, and none developed with either goniotomy or trabeculotomy.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Angiomatosis / complications*
  • Child
  • Child, Preschool
  • Follow-Up Studies
  • Glaucoma / drug therapy
  • Glaucoma / etiology
  • Glaucoma / surgery*
  • Humans
  • Infant
  • Intraocular Pressure / drug effects
  • Laser Therapy
  • Ophthalmic Solutions / therapeutic use*
  • Prognosis
  • Retrospective Studies
  • Sturge-Weber Syndrome / complications*
  • Trabeculectomy
  • Visual Acuity

Substances

  • Ophthalmic Solutions