Horizontal guided bone regeneration in the posterior maxilla using recombinant human platelet-derived growth factor: a case report

Int J Periodontics Restorative Dent. Jul-Aug 2013;33(4):421-5. doi: 10.11607/prd.1408.

Abstract

This clinical case report describes and demonstrates the successful use of purified recombinant human platelet-derived growth factor in conjunction with autogenous bone, an organic bovine bone-derived mineral, and a barrier membrane to reconstruct severe alveolar bone defects. Significant horizontal bone regeneration was achieved in the posterior maxillary region. Three implants were placed into the newly formed ridge and demonstrated stable crestal bone after 36 months of loading.

Publication types

  • Case Reports

MeSH terms

  • Alveolar Ridge Augmentation / methods
  • Angiogenesis Inducing Agents / therapeutic use*
  • Animals
  • Autografts / transplantation
  • Becaplermin
  • Bone Regeneration / physiology*
  • Bone Substitutes / therapeutic use
  • Bone Transplantation / methods
  • Cattle
  • Collagen
  • Crowns
  • Dental Implantation, Endosseous / methods
  • Dental Implants
  • Dental Prosthesis, Implant-Supported
  • Female
  • Follow-Up Studies
  • Guided Tissue Regeneration, Periodontal / methods*
  • Heterografts / transplantation
  • Humans
  • Maxilla / surgery*
  • Membranes, Artificial
  • Middle Aged
  • Minerals / therapeutic use
  • Proto-Oncogene Proteins c-sis / therapeutic use*
  • Recombinant Proteins

Substances

  • Angiogenesis Inducing Agents
  • Bio-Gide
  • Bio-Oss
  • Bone Substitutes
  • Dental Implants
  • Membranes, Artificial
  • Minerals
  • Proto-Oncogene Proteins c-sis
  • Recombinant Proteins
  • Becaplermin
  • Collagen