doi: 10.1007/978-1-62703-484-5_17.
High-throughput screening using dengue virus reporter genomes
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- PMID: 23821271
- DOI: 10.1007/978-1-62703-484-5_17
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High-throughput screening using dengue virus reporter genomes
Methods Mol Biol.
2013.
Abstract
Large-scale antiviral drug discovery and systematic identification of host factors promoting or restricting virus replication require robust, scalable, and cost-effective assay systems that allow for high throughput and automation. Here we describe the construction and application of full-length infectious dengue virus reporter genomes for such screening applications.
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