Decoding a chain letter for degradation

Structure. 2013 Jul 2;21(7):1068-70. doi: 10.1016/j.str.2013.06.009.


Ubiquitin chains can have distinct signaling outcomes, depending on their conjugation point. In this issue of Structure, Castañeda and colleagues describe a new structure of K11 diubiquitin and investigate its recognition by effectors to target substrates to the proteasome.

Publication types

  • Comment

MeSH terms

  • Humans
  • Polyubiquitin / chemistry*


  • Polyubiquitin