Evaluation of a new commercially available immunoglobulin M capture enzyme-linked immunosorbent assay for diagnosis of dengue virus infection

J Clin Microbiol. 2013 Sep;51(9):3102-6. doi: 10.1128/JCM.00351-13. Epub 2013 Jul 3.


We evaluated the FDA-cleared InBios dengue virus (DENV) IgM capture enzyme-linked immunosorbent assay (ELISA) for qualitative detection of anti-DENV IgM antibodies from 79 serum samples obtained from dengue virus-infected patients or suspected dengue cases. The agreement, sensitivity, and specificity of the InBios assay compared to the gold standard in-house DENV IgM capture ELISA were 94, 92, and 94%, respectively. We conclude that the InBios DENV IgM capture ELISA can be effectively used for rapid diagnosis of acute or recent DENV infection.

Publication types

  • Comparative Study
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Antibodies, Viral / blood*
  • Clinical Laboratory Techniques / methods*
  • Dengue / diagnosis*
  • Dengue Virus / immunology*
  • Enzyme-Linked Immunosorbent Assay / methods
  • Humans
  • Immunoglobulin M / blood*
  • Sensitivity and Specificity


  • Antibodies, Viral
  • Immunoglobulin M