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. 2013 Dec;12(6):906-15.
doi: 10.1007/s12311-013-0504-9.

Volumetric Analysis of Regional Variability in the Cerebellum of Children With Dyslexia

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Free PMC article

Volumetric Analysis of Regional Variability in the Cerebellum of Children With Dyslexia

Vindia G Fernandez et al. Cerebellum. .
Free PMC article

Abstract

Cerebellar deficits and subsequent impairment in procedural learning may contribute to both motor difficulties and reading impairment in dyslexia. We used quantitative magnetic resonance imaging to investigate the role of regional variation in cerebellar anatomy in children with single-word decoding impairments (N = 23), children with impairment in fluency alone (N = 8), and typically developing children (N = 16). Children with decoding impairments (dyslexia) demonstrated no statistically significant differences in overall grey and white matter volumes or cerebellar asymmetry; however, reduced volume in the anterior lobe of the cerebellum relative to typically developing children was observed. These results implicate cerebellar involvement in dyslexia and establish an important foundation for future research on the connectivity of the cerebellum and cortical regions typically associated with reading impairment.

Conflict of interest statement

Conflict of interest The authors of this manuscript (Vindia G. Fernandez, Karla K. Stuebing, Jenifer Juranek, and Jack M. Fletcher) declare that they have no conflict of interest to disclose.

Figures

Fig. 1
Fig. 1
ac Parcellation units
Fig. 2
Fig. 2
Distribution of volume (corrected for cerebellar volume) in anterior lobe of cerebellum by group

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