Oxalate nephropathy due to 'juicing': case report and review

Am J Med. 2013 Sep;126(9):768-72. doi: 10.1016/j.amjmed.2013.03.019. Epub 2013 Jul 3.


A patient presented with oxalate-induced acute renal failure that was attributable to consumption of oxalate-rich fruit and vegetable juices obtained from juicing. We describe the case and also review the clinical presentation of 65 patients seen at Mayo Clinic (Rochester, MN) from 1985 through 2010 with renal failure and biopsy-proven renal calcium oxalate crystals. The cause of renal oxalosis was identified for all patients: a single cause for 36 patients and at least 2 causes for 29 patients. Three patients, including our index patient, had presumed diet-induced oxalate nephropathy in the context of chronic kidney disease. Identification of calcium oxalate crystals in a kidney biopsy should prompt an evaluation for causes of renal oxalosis, including a detailed dietary history. Clinicians should be aware that an oxalate-rich diet may potentially precipitate acute renal failure in patients with chronic kidney disease. Juicing followed by heavy consumption of oxalate-rich juices appears to be a potential cause of oxalate nephropathy and acute renal failure.

Keywords: Acute renal failure; Hyperoxalosis; Hyperoxaluria; Nephrotoxicity; Renal transplant.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Acute Kidney Injury / etiology*
  • Aged, 80 and over
  • Biopsy
  • Diet*
  • Fruit*
  • Humans
  • Hyperoxaluria / etiology*
  • Male
  • Oxalates / analysis*
  • Vegetables*


  • Oxalates