Efficacy of an oral appliance for the treatment of obstructive sleep apnea

Int J Prosthodont. Jul-Aug 2013;26(4):334-9. doi: 10.11607/ijp.3284.


Purpose: The aim of this study was to validate the use of a mandibular repositioner appliance (MRA) to treat obstructive sleep apnea (OSA) and primary snoring, comparing polysomnographic and Epworth Sleepiness Scale (ESS) data obtained prior to and during MRA treatment.

Materials and methods: Sixty-three patients who presented with different degrees of OSA severity or primary snoring were fitted to a PM positioner between 2009 and 2011. The diagnosis was established by a polysomnogram (PSG) prior to treatment and after 6 months to verify the efficacy of MRA therapy. Subjective daytime sleepiness was evaluated by ESS questionnaire prior to treatment and at the follow-up.

Results: Patients were divided into primary snoring and OSA groups. For the primary snoring group, PSG variables did not show significant results, except for a decrease in snoring. For the OSA group, the mean apnea-hypopnea index (AHI) was reduced from 23.0 ± 11 to 5.3 ± 4.0 and median ESS reduced significantly from 13.0 to 8.5. Complete response (AHI < 5) was found in 25 (40%) patients and partial response (AHI ≤ 10) in 27 (43%) patients.

Conclusion: The findings validate the efficacy of the adjustable PM positioner for the safe treatment of OSA.

Publication types

  • Clinical Trial
  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Airway Obstruction / therapy
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Mandibular Advancement / instrumentation*
  • Middle Aged
  • Orthodontic Appliance Design*
  • Patient Satisfaction
  • Polysomnography
  • Prospective Studies
  • Remission Induction
  • Reproducibility of Results
  • Sleep Apnea, Obstructive / therapy*
  • Sleep Stages / physiology
  • Snoring / therapy
  • Treatment Outcome