Endless paces of degeneration--applying comparative genomics to study evolution's moulding of longevity

João Pedro de Magalhães; Michael Kean

doi:10.1038/embor.2013.96

Endless paces of degeneration--applying comparative genomics to study evolution's moulding of longevity

EMBO Rep. 2013 Aug;14(8):661-2. doi: 10.1038/embor.2013.96. Epub 2013 Jul 12.

Authors

João Pedro de Magalhães¹, Michael Kean

Affiliation

¹ Integrative Genomics of Ageing Group, Institute of Integrative Biology, University of Liverpool, Liverpool, UK. jp@senescence.info

Abstract

Why do mice and humans have such different lifespans? Genome sequencing efforts are allowing researchers to pick apart the genetic foundations of longevity, with some promising results beginning to emerge.

Publication types

Comparative Study

MeSH terms

Adaptation, Physiological
Animals
Biological Evolution
Chiroptera
DNA Damage
DNA Repair / genetics*
Genomics
Humans
Longevity / genetics*
Mice
Sequence Analysis, DNA
Species Specificity