The introduction of sulfur atoms onto target molecules is an important area in organic synthesis, in particular in the synthesis of pharmaceutical compounds, and a wide variety of sulfuration agents have been developed for thionation reactions over the past few decades. In this Focus Review, we collect and summarize the C-S bond-formation reactions that have been used to construct C-S bonds in natural products and pharmaceutical compounds.
Keywords: cross-coupling; drug design; heterocycles; natural products; sulfur.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.