The impact of zolpidem on the mental status of hospitalized patients older than age 50

Medsurg Nurs. 2013 May-Jun;22(3):188-91, 187.

Abstract

Introduction: Although zolpidem is prescribed widely, determining the incidence of adverse drug reactions such as mental confusion is of considerable clinical importance for nursing practice.

Purpose: The purpose of this study was to examine the use of zolpidem in a hospital setting to determine the incidence of mental confusion for patients receiving the drug.

Method: A correlational cross-sectional study design was used to examine the effects of zolpidem on hospitalized patients. Data abstraction from medical records was used to collect demographic and variable information.

Findings: The first mental status assessment showed no statistical difference of decline in mental status (p=0.08). There was, however, a significant change (p<0.000) after the second mental status assessment.

Conclusion: Based on the results of this study, caution must be considered for first-time users of zolpidem who are greater than age 50.

MeSH terms

  • Age Distribution
  • Aged
  • Aged, 80 and over
  • Confusion / chemically induced*
  • Confusion / epidemiology
  • Cross-Sectional Studies
  • Female
  • Hospitalization
  • Humans
  • Hypnotics and Sedatives / adverse effects*
  • Male
  • Middle Aged
  • Pyridines / adverse effects*
  • Sleep Initiation and Maintenance Disorders / drug therapy*
  • Southeastern United States / epidemiology
  • Zolpidem

Substances

  • Hypnotics and Sedatives
  • Pyridines
  • Zolpidem