Probiotics from research to market: the possibilities, risks and challenges

Curr Opin Microbiol. 2013 Jun;16(3):284-92. doi: 10.1016/j.mib.2013.06.008. Epub 2013 Jul 15.


Probiotic foods can affect large parts of the population, while therapeutic applications have a less wide scope. While commercialization routes and regulatory requirements differ for both applications, both will need good scientific support. Today, probiotics are mainly used for gastrointestinal applications, their use can easily be extended to skin, oral and vaginal health. While most probiotics currently belong to food-grade species, the future may offer new functional microorganisms in food and pharma. This review discusses the crosstalk between probiotic producers, regulatory people, medical care and healthcare workers, and the scientific community.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Biological Therapy / methods*
  • Biological Therapy / standards
  • Diet / methods*
  • Diet / standards
  • Drug Approval
  • Humans
  • Probiotics / adverse effects
  • Probiotics / pharmacology
  • Probiotics / therapeutic use*