Differential survival improvement for patients 20-29 years of age with acute lymphoblastic leukemia

Leuk Res. 2013 Oct;37(10):1258-64. doi: 10.1016/j.leukres.2013.05.001. Epub 2013 Jul 16.

Abstract

Objective: To compare improvement in survival from 1986 to 2009 for acute lymphoblastic leukemia (ALL) patients 1-14, 15-19 and 20-29 years in Ontario and United States.

Methods: This population-based analysis used data from Ontario Cancer Registry (OCR) and Surveillance Epidemiology and End Results (SEER).

Results: In OCR, there was steady improvement in survival by period of diagnosis in all three age groups. In SEER, there was no improvement in survival for patients aged 20-29 years.

Conclusions: Survival in Ontario and the United States has improved for patients with ALL aged 1-19 years. However, survival has improved among patients aged 20-29 years only in Ontario.

Keywords: Acute lymphoblastic leukemia; Adolescent and young adult; Cancer; OCR; SEER; Survival.

Publication types

  • Historical Article
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Child
  • Child, Preschool
  • Female
  • History, 20th Century
  • History, 21st Century
  • Humans
  • Infant
  • Male
  • Ontario / epidemiology
  • Population Surveillance
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / epidemiology
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / history
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / mortality*
  • Registries
  • SEER Program
  • United States / epidemiology
  • Young Adult