Bisphosphonate-related osteonecrosis of the jaws and its relevance to children--a review

Joanna Christou; Adele R Johnson; Tim A Hodgson

doi:10.1111/ipd.12047

Bisphosphonate-related osteonecrosis of the jaws and its relevance to children--a review

Int J Paediatr Dent. 2013 Sep;23(5):330-7. doi: 10.1111/ipd.12047. Epub 2013 Jul 21.

Authors

Joanna Christou¹, Adele R Johnson, Tim A Hodgson

Affiliation

¹ Department of Oral Medicine, Eastman Dental Hospital and Eastman Dental Institute, UCLHT UCL, London, UK.

PMID: 23869707
DOI: 10.1111/ipd.12047

Abstract

Bisphosphonate-related osteonecrosis of the jaws (BRONJ) has been detailed extensively in adults, but to date, there have been no similar cases in children. Members of the dental team may treat children prescribed bisphosphonate therapy often for management of osteogenesis imperfecta (OI). There is uncertainty as to how best treat this patient group. This review explores the background of bisphosphonates, indications for their prescription in children, adverse effects with special emphasis on BRONJ, and protocols available to guide dental management.

Publication types

Review

MeSH terms

Bisphosphonate-Associated Osteonecrosis of the Jaw / diagnosis
Bisphosphonate-Associated Osteonecrosis of the Jaw / etiology*
Bisphosphonate-Associated Osteonecrosis of the Jaw / prevention & control
Child
Diphosphonates / adverse effects*
Humans
Osteogenesis Imperfecta / drug therapy*
Risk Factors

Substances

Diphosphonates