A rare case of synchronous fetal type adenocarcinoma and mucinous adenocarcinoma of the lung evaluated by 18F-FDG PET/CT

Clin Nucl Med. 2014 Aug;39(8):e384-6. doi: 10.1097/RLU.0b013e31829a0199.


A 71-year-old man underwent F-FDG PET/CT for metabolic characterization of pulmonary nodules. F-FDG PET/CT showed increased tracer uptake in a 3.5-cm left upper lobe mass. A second lesion (1.5 cm) characterized by poor F-FDG uptake was described in the same lobe. Based on these findings, the patient underwent upper left lobectomy. Histology demonstrated 2 synchronous tumors. The F-FDG-avid lesion was a rare moderately differentiated fetal type adenocarcinoma, whereas the second lesion with low F-FDG uptake was a moderately differentiated mucinous adenocarcinoma. In our case, F-FDG PET/CT has been useful in metabolic characterization and staging of these synchronous rare pulmonary tumors.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / diagnostic imaging*
  • Adenocarcinoma of Lung
  • Adenocarcinoma, Mucinous / diagnostic imaging*
  • Aged
  • Fluorodeoxyglucose F18
  • Humans
  • Lung Neoplasms / diagnostic imaging*
  • Male
  • Multimodal Imaging*
  • Multiple Pulmonary Nodules / diagnostic imaging*
  • Positron-Emission Tomography*
  • Radiopharmaceuticals
  • Tomography, X-Ray Computed*


  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18