Abstract
In many eukaryotes, cytokinesis requires an actomyosin contractile ring that is crucial for cell constriction and new membrane organization. Two studies in this issue (Onishi et al. 2013. J. Cell Biol. http://dx.doi.org.10.1083/jcb.201302001 and Atkins et al. 2013. J. Cell Biol. http://dx.doi.org.10.1083/jcb.201301090) establish that precise activation and/or inactivation of Rho1 and Cdc42 GTPases is important for the correct order and successful completion of events downstream of actomyosin ring constriction in budding yeast.
Publication types
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Research Support, Non-U.S. Gov't
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Comment
MeSH terms
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Cytokinesis*
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Microtubule-Associated Proteins / metabolism*
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Mitosis*
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Saccharomyces cerevisiae Proteins / metabolism*
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Saccharomycetales / enzymology*
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cdc42 GTP-Binding Protein, Saccharomyces cerevisiae / metabolism*
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rho GTP-Binding Proteins / metabolism*
Substances
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Cyk3 protein, S cerevisiae
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Microtubule-Associated Proteins
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Saccharomyces cerevisiae Proteins
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RHO1 protein, S cerevisiae
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cdc42 GTP-Binding Protein, Saccharomyces cerevisiae
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rho GTP-Binding Proteins