Uterus transplantation from a deceased donor

Fertil Steril. 2013 Dec;100(6):e41. doi: 10.1016/j.fertnstert.2013.06.041. Epub 2013 Jul 21.


Objective: To demonstrate the technique for uterus retrieval and transplantation from a multiorgan donor.

Design: Video presentation of our case report. The video uses animation to demonstrate the technique. Institutional Review Board (IRB) approval was obtained.

Setting: University hospital.

Patient(s): A 21-year-old woman with complete müllerian agenesis.

Intervention(s): Uterus allotransplantation has been performed from a deceased donor.

Main outcome measure(s): Acquirement of cyclic menstrual function.

Result(s): This video demonstrates the technique for uterus retrieval, perfusion, and transplantation. The recipient patient has been monitored regularly for vascular flow, immunosuppression, and infection control since the operation.

Conclusion(s): Uterus transplantation requires extensive evaluation of the recipient and donor by an experienced multidisciplinary transplantation team both pre- and postoperatively. It has major risks related to surgery, immunosuppression, and pregnancy. Uterus transplantation might be considered promising only after the birth of a near-term healthy baby.

Keywords: Uterus transplantation; deceased donor; uterine factor infertility.

Publication types

  • Case Reports
  • Video-Audio Media

MeSH terms

  • 46, XX Disorders of Sex Development / complications
  • 46, XX Disorders of Sex Development / diagnosis*
  • 46, XX Disorders of Sex Development / surgery*
  • Adult
  • Amenorrhea / diagnosis*
  • Amenorrhea / etiology
  • Amenorrhea / prevention & control*
  • Congenital Abnormalities / diagnosis*
  • Congenital Abnormalities / surgery*
  • Female
  • Humans
  • Mullerian Ducts / abnormalities*
  • Mullerian Ducts / surgery
  • Treatment Outcome
  • Unrelated Donors
  • Uterus / transplantation*

Supplementary concepts

  • Mullerian aplasia