The Drosophila visual system: From neural circuits to behavior

Cell Adh Migr. 2013 Jul-Aug;7(4):333-44. doi: 10.4161/cam.25521. Epub 2013 Jun 27.

Abstract

A compact genome and a tiny brain make Drosophila the prime model to understand the neural substrate of behavior. The neurogenetic efforts to reveal neural circuits underlying Drosophila vision started about half a century ago, and now the field is booming with sophisticated genetic tools, rich behavioral assays, and importantly, a greater number of scientists joining from different backgrounds. This review will briefly cover the structural anatomy of the Drosophila visual system, the animal's visual behaviors, the genes involved in assembling these circuits, the new and powerful techniques, and the challenges ahead for ultimately identifying the general principles of biological computation in the brain.

Keywords: Drosophila; behavior; neural circuits; neurogenetics; vision.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Behavior, Animal / physiology
  • Drosophila / metabolism*
  • Drosophila / physiology*
  • Drosophila Proteins / metabolism
  • Nervous System / metabolism*

Substances

  • Drosophila Proteins