Soy fiber improves weight loss and lipid profile in overweight and obese adults: a randomized controlled trial

Mol Nutr Food Res. 2013 Dec;57(12):2147-54. doi: 10.1002/mnfr.201300159. Epub 2013 Jul 23.


Scope: Studies have suggested that food rich in dietary fiber may facilitate body weight loss, lower total and LDL-cholesterol levels, and reduce body fat. This study examined the effects of soy fiber (SF) on body weight, body composition, and blood lipids in overweight and obese participants.

Methods and results: Thirty-nine overweight and obese college adults (19-39 years of age) were randomly assigned to consume control biscuits or biscuits supplemented with SF for their breakfast for 12 wk (approximately 100 g/day). There were significant differences in changes on body weight, BMI, and LDL-cholesterol (LDL-C) between the two groups after 12-wk intervention (p < 0.05). The changes of body weight, BMI, waist circumference, diastolic blood pressure, serum levels of total cholesterol, LDL-C, and glucose, body fat, and trunk fat of participants in SF group were observed significantly after 12 wk.

Conclusion: SF had favorable effects on body weight, BMI, and fasting LDL-C levels in overweight and obese adults. These effects may be beneficial in antiobesity and the improvement of hyperlipidemia and hypertension ( registration number-NCT01802840).

Keywords: Body fat; Cholesterol; Obesity; Soy fiber; Weight loss.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adipose Tissue / drug effects
  • Adult
  • Anti-Obesity Agents / therapeutic use*
  • Blood Pressure
  • Cholesterol / blood
  • Cholesterol, LDL / blood
  • Dietary Fiber / therapeutic use*
  • Female
  • Humans
  • Lipid Metabolism / drug effects*
  • Male
  • Obesity / diet therapy*
  • Obesity / metabolism
  • Overweight / diet therapy*
  • Soybeans
  • Waist Circumference / drug effects
  • Young Adult


  • Anti-Obesity Agents
  • Cholesterol, LDL
  • Dietary Fiber
  • Cholesterol

Associated data