HLA-B27 positive idiopathic acute anterior uveitis: a unique manifestation of subclinical gut inflammation

J Rheumatol. 1990 Jun;17(6):841-2.


Ileocolonoscopy was performed on 2 HLA-B27 positive patients with idiopathic acute anterior uveitis neither of whom had articular or intestinal complaints. Microscopic examination of the biopsy specimens revealed the presence of chronic inflammatory lesions in the ileum. Since these lesions have also been described in other forms of spondyloarthropathy, we postulate the presence of gut inflammation was related to the uveitis.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Adult
  • Colonoscopy
  • Female
  • Gastrointestinal Diseases / complications
  • Gastrointestinal Diseases / pathology
  • HLA-B27 Antigen / immunology*
  • Humans
  • Ileum / pathology
  • Inflammation / complications
  • Inflammation / pathology
  • Uveitis, Anterior / etiology
  • Uveitis, Anterior / immunology*
  • Uveitis, Anterior / pathology


  • HLA-B27 Antigen