Imaging tumor angiogenesis: the road to clinical utility

AJR Am J Roentgenol. 2013 Aug;201(2):W183-91. doi: 10.2214/AJR.12.8568.

Abstract

Objective: Tumor growth and progression require the formation of new blood vessels from preexisting vasculature, a process called angiogenesis. The ability to noninvasively visualize angiogenesis may provide new opportunities to more appropriately select patients for antiangiogenesis treatment and to monitor treatment efficacy.

Conclusion: The superior molecular sensitivity of PET and the lack of radiation from MRI and contrast-enhanced ultrasound put these techniques at the forefront of clinical translation.

Publication types

  • Review

MeSH terms

  • Angiogenesis Inhibitors / therapeutic use
  • Contrast Media
  • Diagnostic Imaging*
  • Disease Progression
  • Humans
  • Neovascularization, Pathologic / diagnosis*
  • Neovascularization, Pathologic / drug therapy
  • Neovascularization, Pathologic / pathology

Substances

  • Angiogenesis Inhibitors
  • Contrast Media