An abnormal elevation of serum CA72-4 by ganoderma lucidum spore powder

Ann Clin Lab Sci. 2013 Summer;43(3):337-40.


We reported three patients with an abnormal elevation of serum CA72-4 levels when taking GLSP, which is commonly used as a dietary supplement for cancer patients across the globe. Furthermore, the results were not due to the apparent analytical interference. In case 1 and case 2, excessive examinations were carried out because of a lack of timely communication with patients when the abnormal elevation of CA724 was found. In contrast, the lesson from these two cases made us communicate with the patient in a timely manner in Case 3, avoiding unnecessary examinations when the same situation happened. Therefore, it is necessary to communicate with patients in a timely manner once an abnormal elevation of serum CA72-4 is found.

Keywords: CA724; ganoderma lucidum; interference.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Antigens, Tumor-Associated, Carbohydrate / blood*
  • Biomarkers, Tumor / blood*
  • Female
  • Humans
  • Middle Aged
  • Powders / administration & dosage
  • Powders / pharmacology*
  • Prognosis
  • Reishi / chemistry*
  • Spores, Fungal / physiology*
  • Stomach Neoplasms / blood
  • Stomach Neoplasms / drug therapy
  • Stomach Neoplasms / pathology*


  • Antigens, Tumor-Associated, Carbohydrate
  • Biomarkers, Tumor
  • CA-72-4 antigen
  • Powders