Observation of the long-term effects of lifestyle intervention during balneotherapy in metabolic syndrome

Therapie. 2013 May-Jun;68(3):163-7. doi: 10.2515/therapie/2013025. Epub 2013 Jul 26.


Objective: Estimate the effect of lifestyle adjustment activities in patients with metabolic syndrome treated by prescribed balneotherapy.

Methods: Observational pilot cohort study with 12-month follow-up after multidimensional lifestyle training (physical, dietary, educational) during 3-week standard stay in the spa town of Eugénie-les-Bains.

Results: Of 145 eligible patients, 97 were included; 63 were followed and analysable. At inclusion all had ≥3 National cholesterol education program-Adult treatment panel III (NCEP-ATPIII) criteria defining metabolic syndrome, 76.2% were female, mean age was 61.2 years. At the end of follow-up (median:10.4 months, Inter-Quartile Range: [6.7;11.4]), 48 of these 63 patients (76.2%) no longer had metabolic syndrome (95%CI [65.7;86.7]). These 48 patients without metabolic syndrome at the end of follow-up represented 49.5% of the 97 included (95%CI [39.5;59.4]).

Conclusions: Future studies of lifestyle interventions taking advantage of the spa environment can be expected to find least one third of patients free of metabolic syndrome at the end of 12-month follow-up in the intervention group.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Anthropometry
  • Balneology*
  • Blood Glucose / analysis
  • Blood Pressure
  • Combined Modality Therapy
  • Diet, Reducing
  • Exercise Therapy
  • Female
  • Follow-Up Studies
  • Health Resorts*
  • Humans
  • Life Style*
  • Lipids / blood
  • Male
  • Metabolic Syndrome / blood
  • Metabolic Syndrome / diet therapy
  • Metabolic Syndrome / therapy*
  • Middle Aged
  • Motivation
  • Patient Education as Topic
  • Pilot Projects
  • Prospective Studies
  • Treatment Outcome
  • Weight Loss


  • Blood Glucose
  • Lipids