Painless ascites and elevated CA125: initial presentation of lupus-associated protein-losing enteropathy

C S Ong; T E Cheah; R Jasmin; F Yahya; S Sockalingam; C T Ng

doi:10.1177/0961203313498792

Painless ascites and elevated CA125: initial presentation of lupus-associated protein-losing enteropathy

Lupus. 2013 Oct;22(11):1174-7. doi: 10.1177/0961203313498792. Epub 2013 Jul 25.

Authors

C S Ong¹, T E Cheah, R Jasmin, F Yahya, S Sockalingam, C T Ng

Affiliation

¹ Division of Rheumatology, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

PMID: 23886639
DOI: 10.1177/0961203313498792

Abstract

Lupus associated protein loosing enteropathy (LUPLE) is a rare gastrointestinal manifestation of SLE. We presented a case of painless ascites from serve hypoalbuminaemia secondary to LUPLE. The patient responded to a course of intravenous cyclophosphamide. The remission was maintained by azathioprine and low dose prednisolone.

Keywords: CA125; Systemic lupus erythematosus; ascites; protein-losing enteropathy.

Publication types

Case Reports

MeSH terms

Ascites / etiology*
Azathioprine / therapeutic use
CA-125 Antigen / blood*
Cyclophosphamide / therapeutic use
Female
Humans
Lupus Erythematosus, Systemic / complications*
Middle Aged
Prednisolone / therapeutic use
Protein-Losing Enteropathies / diagnosis*
Protein-Losing Enteropathies / drug therapy
Protein-Losing Enteropathies / etiology

Substances

CA-125 Antigen
Cyclophosphamide
Prednisolone
Azathioprine