Predictive factors of successful redo varicocelectomy in infertile patients with recurrent varicocele

Andrologia. 2014 Sep;46(7):738-43. doi: 10.1111/and.12142. Epub 2013 Jul 28.

Abstract

To examine the predictive factors of successful redo varicocelectomy in infertile patients with recurrent varicocele, we made a retrospective study. Twenty-one patients who had improved quality of spermatozoon 6 months after RV were designated as group 1, those with no improvement as group 2 (17 subjects) and those who received close surveillance as group 3 (10 patients) were recruited. The predictive factors included were time to recurrent varicocele; semen quality; testicular volume; number of ligated veins; body mass index; serum levels of follicle-stimulating hormone (FSH), luteinising hormone and testosterone; scrotal temperature; and peak retrograde flow (PRF) and maximal vein diameter (MVD) by colour Doppler ultrasound. The quality of spermatozoon improved significantly 6 months after RV in group 1 patients (21, 55.3%), and no improvement in group 2 and 3 patients. Patients in group 1 also had significantly lower FSH and PRF, longer time to recurrent varicocele, higher number of ligated veins and larger testicular volume than the group 2 (17, 44.7%) and group 3 patients. The significant predictive factors of successful RV were lower FSH and PRF; longer time to recurrent varicocele; and larger testicular volume preoperatively and a higher number of ligated veins during redo varicocelectomy.

Keywords: FSH; redo varicocelectomy; testicular volume; varicocele.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Follicle Stimulating Hormone / blood
  • Humans
  • Infertility, Male / complications*
  • Luteinizing Hormone / blood
  • Male
  • Recurrence
  • Testosterone / blood
  • Ultrasonography, Doppler, Color
  • Varicocele / complications
  • Varicocele / surgery*

Substances

  • Testosterone
  • Luteinizing Hormone
  • Follicle Stimulating Hormone