Spindle Orientation: Timing Is Everything

Neuron. 2013 Jul 24;79(2):211-3. doi: 10.1016/j.neuron.2013.07.005.

Abstract

In this issue of Neuron, Xie et al. (2013) identified protein phosphatase 4c (PP4c) as a new component in the regulation of spindle orientation during mammalian neurogenesis. Importantly, their findings uncovered a novel and critical temporal aspect of the regulation of spindle orientation during neurogenesis.

Publication types

  • Comment

MeSH terms

  • Animals
  • Cell Proliferation*
  • Female
  • Neocortex / embryology*
  • Neocortex / enzymology*
  • Neurogenesis / physiology*
  • Phosphoprotein Phosphatases / physiology*
  • Pregnancy
  • Spindle Apparatus / enzymology*

Substances

  • Phosphoprotein Phosphatases
  • protein phosphatase 4