Virulence, Genomic Features, and Plasticity of Aeromonas Salmonicida Subsp. Salmonicida, the Causative Agent of Fish Furunculosis

Vet Microbiol. 2014 Feb 21;169(1-2):1-7. doi: 10.1016/j.vetmic.2013.06.025. Epub 2013 Jul 9.

Abstract

The bacterium Aeromonas salmonicida subsp. salmonicida is the causative agent of furunculosis, a systemic disease of fish in the salmonid family. Furunculosis is a ubiquitous disease that affects aquaculture operations worldwide and is characterized by high mortality and morbidity. A better understanding of the bacterium is required to find a cure. Thereby, this review centers on A. salmonicida subsp. salmonicida, its major virulence factors, and its genome. The classification and characteristics of A. salmonicida subsp. salmonicida, the virulence factors, such as the A-layer, extracellular molecules, and type three secretion system as well as the characteristics and plasticity of its genome are described.

Keywords: Aeromonas salmonicida; Antibiotic resistance; Furunculosis; Genome; Insertion sequences; Plasmid; Type three secretion system; Virulence.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Aeromonas salmonicida / genetics*
  • Aeromonas salmonicida / pathogenicity*
  • Aeromonas salmonicida / physiology
  • Animals
  • Bacterial Proteins / genetics
  • Bacterial Proteins / metabolism
  • Bacterial Secretion Systems / physiology
  • Fish Diseases / microbiology*
  • Furunculosis / microbiology
  • Furunculosis / veterinary*
  • Genome, Bacterial*
  • Salmonidae / microbiology*
  • Virulence / genetics
  • Virulence Factors / genetics
  • Virulence Factors / metabolism

Substances

  • Bacterial Proteins
  • Bacterial Secretion Systems
  • Virulence Factors