Update in the treatment of high-grade Gliomas

Neurol Clin. 2013 Aug;31(3):847-67. doi: 10.1016/j.ncl.2013.03.005. Epub 2013 Apr 6.

Abstract

Advances in the molecular classification of high-grade gliomas are laying the groundwork for potential changes in the treatment of high-grade gliomas. Currently, a combined modality approach involving surgery, radiation therapy, and chemotherapy is most often used in the treatment of high-grade gliomas. The authors review recent advances in the treatment of these primary brain tumors.

Keywords: Chemotherapy; Gliomas; Radiation therapy; Surgery.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Antineoplastic Agents / therapeutic use
  • Brain Neoplasms / genetics
  • Brain Neoplasms / therapy*
  • Dacarbazine / analogs & derivatives
  • Dacarbazine / therapeutic use
  • Drug Therapy, Combination
  • Glioma / genetics
  • Glioma / therapy*
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Radiotherapy
  • Temozolomide

Substances

  • Antineoplastic Agents
  • Dacarbazine
  • Temozolomide