Comparative study on bruise reduction treatments after bruise induction using the pulsed dye laser

Dermatol Surg. 2013 Oct;39(10):1459-64. doi: 10.1111/dsu.12293. Epub 2013 Jul 30.

Abstract

Background: Several bruise reduction methods have been suggested to decrease postprocedure ecchymoses. Comparing the effectiveness of common bruise reduction therapies provides better evidence of the efficacy of bruise reduction techniques.

Objective: To compare the effectiveness of cold compresses, hydrogen peroxide, over-the-counter bruise serum, and pulsed dye laser (PDL) in minimizing the time required for bruise resolution.

Methods: Seventeen patients aged 22 to 51 (mean 28) with Fitzpatrick skin types I to IV underwent bruise induction with a PDL to produce five 2- by 2-cm zones of bruising on the lower abdomen. Excluding the control, bruises were randomly treated using a cold compress, bruise serum, 3% hydrogen peroxide-soaked gauze, or PDL. Subjects and two blinded physician evaluators evaluated bruise severity and graded it on a visual analog scale on days 0, 3, and 7.

Results: Treatment did not result in statistically significantly shorter bruise resolution time than in controls. PDL-treated bruises took a statistically significantly longer time to resolve than controls.

Conclusion: Our study showed no significant difference in cold compress, hydrogen peroxide, and over-the-counter serum in reducing time to bruise resolution. PDL therapy resulted in greater bruise severity scores and increased time to bruise resolution when used soon after bruise induction.

Publication types

  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Contusions / etiology
  • Contusions / therapy*
  • Cryotherapy
  • Dermatologic Agents / therapeutic use
  • Drug Combinations
  • Ecchymosis / etiology
  • Ecchymosis / therapy*
  • Female
  • Glycerol / therapeutic use
  • Humans
  • Hydrogen Peroxide / therapeutic use
  • Lasers, Dye / adverse effects
  • Lasers, Dye / therapeutic use
  • Linoleic Acids / therapeutic use
  • Male
  • Middle Aged
  • Oenothera biennis
  • Oxidants / therapeutic use
  • Plant Oils / therapeutic use
  • Single-Blind Method
  • Time Factors
  • Trauma Severity Indices
  • Vitamin E / therapeutic use
  • Young Adult
  • gamma-Linolenic Acid / therapeutic use

Substances

  • Dermatologic Agents
  • Drug Combinations
  • Linoleic Acids
  • Oxidants
  • Plant Oils
  • Vitamin E
  • evening primrose oil
  • gamma-Linolenic Acid
  • Hydrogen Peroxide
  • Glycerol