Nonmedical use of prescription ADHD stimulant medications among adults in a substance abuse treatment population: early findings from the NAVIPPRO surveillance system

J Atten Disord. 2015 Apr;19(4):275-83. doi: 10.1177/1087054713493321. Epub 2013 Jul 30.

Abstract

Objective: To examine nonmedical use (NMU) of prescription ADHD stimulants among adults evaluated for substance abuse treatment.

Method: 147,816 assessments from the National Addictions Vigilance Intervention and Prevention Program (NAVIPPRO) system (10/01/2009 through 03/31/2012) examined NMU prevalence, routes of administration (ROA), and diversion sources.

Results: Past 30-day NMU for prescription stimulants (1.29%) was significantly lower than that of prescription opioids (19.79%) or sedatives (10.62%). For stimulant products, NMU for Adderall was 0.62, followed by Adderall XR (0.42), Ritalin (0.16), Vyvanse (0.12), and Concerta (0.08); product differences likely have limited clinical relevance given the low estimates (<1%). Higher NMU per prescriptions was for Adderall (4.92), Ritalin (4.68), and Adderall XR (3.18) compared with newer formulations (Vyvanse 1.26, Concerta 0.89). Diversion source was mainly family/friends with no differences between products; swallowing whole was the most frequent ROA.

Conclusion: Prescription stimulant NMU was low compared with other prescription medications among individuals assessed for substance abuse problems, with little difference among specific products.

Keywords: ADHD; NAVIPPRO; nonmedical use; prescription stimulants; substance abuse.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Amphetamine-Related Disorders / epidemiology
  • Amphetamine-Related Disorders / psychology
  • Attention Deficit Disorder with Hyperactivity / drug therapy
  • Attention Deficit Disorder with Hyperactivity / epidemiology
  • Central Nervous System Stimulants / administration & dosage*
  • Central Nervous System Stimulants / therapeutic use
  • Drug Prescriptions / statistics & numerical data*
  • Female
  • Humans
  • Male
  • Methylphenidate / therapeutic use
  • Middle Aged
  • Prescription Drug Misuse*
  • Prescription Drugs / administration & dosage
  • Prescription Drugs / adverse effects*
  • Prescription Drugs / therapeutic use
  • Prevalence
  • Self Medication / psychology*
  • Substance-Related Disorders / epidemiology
  • Substance-Related Disorders / psychology
  • Substance-Related Disorders / therapy*
  • Young Adult

Substances

  • Central Nervous System Stimulants
  • Prescription Drugs
  • Methylphenidate