Diabesity is a modern epidemic, which indicates the coexistence of both diabetes and obesity. Linked by various pathophysiological mechanisms, revolving around insulin resistance and hyperinsulinaemia, diabesity has important diagnostic and therapeutic implications. This review describes the important associations of diabesity, and highlights the various ono-pharmacological and pharmacological methods of management. It makes a strong call for utilising indigenous, low cost means of enhancing healthy dietary and physical activity habits.