Bad trip due to anticholinergic effect of cannabis

Gen Hosp Psychiatry. Nov-Dec 2013;35(6):682.e5-6. doi: 10.1016/j.genhosppsych.2013.06.010. Epub 2013 Jul 29.


Cannabis in its various forms has been known since time immemorial, the use of which has been rising steadily in India. 'Bad trips' have been documented after cannabis use, manifestations ranging from vague anxiety and fear to profoundly disturbing states of terror and psychosis. Cannabis is known to affect various neurotransmitters, but 'bad trip' due to its anticholinergic effect has never been described in literature to the best of author's knowledge. Hereby, the author describes a case of a young adult male experiencing profound anticholinergic effects after being exposed for the first time in his life to bhang, a local oral preparation of cannabis.

Keywords: Anticholinergic; Bad trip; Bhang; Cannabis.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Akathisia, Drug-Induced / etiology*
  • Anxiety / chemically induced*
  • Cannabis / poisoning*
  • Cholinergic Antagonists / poisoning*
  • Humans
  • Male
  • Tachycardia / chemically induced*
  • Urinary Retention / chemically induced*
  • Xerostomia / chemically induced


  • Cholinergic Antagonists