Amrinone, forerunner of novel cardiotonic agents, caused paradigm shift of heart failure pharmacotherapy

Circ Res. 2013 Aug 2;113(4):358-61. doi: 10.1161/CIRCRESAHA.113.301689.
No abstract available

MeSH terms

  • Amrinone / pharmacology
  • Amrinone / therapeutic use*
  • Animals
  • Calcium Signaling / physiology
  • Cardiotonic Agents / pharmacology
  • Cardiotonic Agents / therapeutic use*
  • Chronic Disease
  • Disease Models, Animal
  • Dogs
  • Drug Therapy / trends*
  • Heart Failure / drug therapy*
  • Heart Failure / physiopathology
  • Phosphodiesterase 3 Inhibitors / pharmacology
  • Phosphodiesterase 3 Inhibitors / therapeutic use
  • Vasodilation / drug effects
  • Vasodilation / physiology

Substances

  • Cardiotonic Agents
  • Phosphodiesterase 3 Inhibitors
  • Amrinone