Abstract
Chemical study of the ethyl acetate extract of the plant endophytic fungus Cladosporium sp. (strain no. IFB3lp-2) yielded three new polyketides (1-3), together with nine known compounds. All of the structures were elucidated on the basis of spectroscopic methods. The isolated compounds were screened for their cytotoxic, antiviral, and acetyl cholinesterase inhibitory activities. Regretfully, no compounds showed any significant activity in these assays.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antiviral Agents / chemistry
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Antiviral Agents / isolation & purification*
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Antiviral Agents / pharmacology
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China
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Cholinesterase Inhibitors / chemistry
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Cholinesterase Inhibitors / isolation & purification*
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Cholinesterase Inhibitors / pharmacology
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Cladosporium / chemistry*
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Drug Screening Assays, Antitumor
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Female
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HCT116 Cells
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Hep G2 Cells
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Humans
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Microbial Sensitivity Tests
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Molecular Structure
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Plant Leaves / microbiology
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Polyketides / chemistry
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Polyketides / isolation & purification*
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Polyketides / pharmacology
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Rhizophoraceae / microbiology
Substances
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Antiviral Agents
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Cholinesterase Inhibitors
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Polyketides