Ethical and legal issues arising in research on inducing human germ cells from pluripotent stem cells

Cell Stem Cell. 2013 Aug 1;13(2):145-8. doi: 10.1016/j.stem.2013.07.005.


Derivation of eggs or sperm from pluripotent stem cells or direct reprogramming from somatic cells would have huge effects on assisted reproductive technology. Here we discuss important ethical, legal, and social issues that would be raised by the development of such female or male gametes for clinical use.

MeSH terms

  • Animals
  • Female
  • Germ Cells / cytology*
  • Humans
  • Internationality
  • Japan
  • Male
  • Mice
  • Pluripotent Stem Cells / cytology*
  • Research Embryo Creation / legislation & jurisprudence
  • Stem Cell Research / ethics*
  • Stem Cell Research / legislation & jurisprudence*