Atypical melanocytic naevi following melanotan injection

Ir Med J. 2013 May;106(5):148-9.


Melanotan is a synthetic analogue of alpha melanocyte stimulating hormone (a-MSH) that stimulates melanogenesis. It is sold on the internet and tanning salons as a quick 'tanning jab'. We report a patient who developed multiple new onset atypical naevi within one week of receiving two Melanotan injections. This case highlights the potential risk of Melanotan in stimulating dysplastic naevi or possibly malignant melanoma.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cosmetics / adverse effects*
  • Dermoscopy
  • Female
  • Humans
  • Nevus, Pigmented / chemically induced*
  • Peptides, Cyclic / adverse effects*
  • Skin Neoplasms / chemically induced*
  • Skin Pigmentation / drug effects
  • alpha-MSH / adverse effects
  • alpha-MSH / analogs & derivatives*


  • Cosmetics
  • Peptides, Cyclic
  • melanotan-II
  • alpha-MSH