Outcome of transcatheter closure of oval shaped atrial septal defect with amplatzer septal occluder

Yonsei Med J. 2013 Sep;54(5):1104-9. doi: 10.3349/ymj.2013.54.5.1104.

Abstract

Purpose: For the successful completion of transcatheter closure of atrial septal defects with the Amplatzer septal occluder, shape of the defects should be considered prior to selecting the device. The purpose of this study is to evaluate the results of a transcatheter closure of oval shaped atrial septal defect.

Materials and methods: From November 2009 until November 2011, cardiac computed tomography was performed on 69 patients who needed a transcatheter closure of atrial septal defect. We defined an oval shaped atrial septal defect as the ratio of the shortest diameter to the longest diameter ≤ 0.75 measured using computed tomography. A trans-thoracic echocardiogram was performed one day after and six months after.

Results: The transcatheter closure of atrial septal defect was performed successfully in 24 patients in the ovoid group and 45 patients in the circular group. There were no serious complications in both groups and the complete closure rate at 6 months later was 92.3% in the ovoid group and 93.1% in the circular group (p>0.05). The differences between the device size to the longest diameter of the defect and the ratios of the device size to the longest diameter were significantly smaller in the ovoid group (1.8 ± 2.8 vs. 3.7 ± 2.6 and 1.1 ± 0.1 vs. 1.2 ± 0.2).

Conclusion: Transcatheter closure of an oval shaped atrial septal defect was found to be safe with the smaller Amplatzer septal occluder device when compared with circular atrial septal defects.

Keywords: Congenital heart disease; atrial septal defect; cardiac computed tomography; device closure; transcatheter intervention.

MeSH terms

  • Echocardiography
  • Heart Septal Defects, Atrial / pathology
  • Heart Septal Defects, Atrial / surgery*
  • Humans
  • Middle Aged
  • Postoperative Complications
  • Republic of Korea
  • Retrospective Studies
  • Septal Occluder Device / adverse effects*
  • Tomography, X-Ray Computed
  • Treatment Outcome