Combined treatment for facial rejuvenation using an optimized pulsed light source followed by a fractional non-ablative laser

Lasers Surg Med. 2013 Sep;45(7):405-9. doi: 10.1002/lsm.22162. Epub 2013 Aug 7.

Abstract

Background: Combination laser treatments can potentially increase the effectiveness of treatment without the additional downtime associated with another procedure.

Objective: To assess the effectiveness and safety of combining non-ablative fractional treatments with optimized intense pulsed light.

Methods and materials: Ten subjects (Group A) received full face treatments with a non-ablative fractional either followed or preceded by an optimized intense pulsed light source. Twenty-six subjects (Group B) received only full face treatments with the same non-ablative, fractional laser device.

Results: For Group A, the overall average Fitzpatrick Wrinkle Scale for all patients improved from 6.3 ± 1.1 at baseline to 5.9 ± 0.8 one month following one treatment for an average improvement of 0.4 ± 0.6 (P < 0.10 paired t-test n = 9). The average pigment improvement score was 1.8 ± 0.9 on a 4-point scale. In Group B, the average Fitzpatrick Wrinkle Scale improved from 6.0 ± 1.6 at baseline to 5.2 ± 1.4 at 3 months for an average improvement of 0.8 ± 0.7 (P < 0.001, n = 26 paired t-test). The average pigment improvement score was 1.4 ± 1.0 (P < 0.001, t-test, n = 26). Adverse events were similar in the two groups.

Conclusion: The combination of an optimized intense pulsed light source with a non-ablative fractional laser during the same treatment session is safe and effective.

Keywords: IPL; combination; facial rejuvenation; fractional; intense pulsed light; laser; non-ablative.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Combined Modality Therapy
  • Cosmetic Techniques*
  • Face
  • Female
  • Follow-Up Studies
  • Humans
  • Intense Pulsed Light Therapy / methods*
  • Lasers, Solid-State / therapeutic use*
  • Middle Aged
  • Outcome and Process Assessment, Health Care
  • Patient Satisfaction
  • Rejuvenation*
  • Skin Aging*
  • Skin Pigmentation*