Bacillus cereus septicemia in a patient with acute lymphoblastic leukemia: A case report and review of the literature

J Microbiol Immunol Infect. 2016 Jun;49(3):448-51. doi: 10.1016/j.jmii.2013.06.010. Epub 2013 Aug 6.

Abstract

Bacillus cereus is an aerobic Gram-positive, spore-forming, rod-shaped bacterium that is responsible for foodborne illnesses. We report on a 15-year-old girl with B-cell acute lymphoblastic leukemia, who fell into a somnolent state after presenting with a 12-hour history of fever, muscle soreness, myalgia in both calves, sore throat, and vomiting. Fulminant septicemic syndrome caused by B. cereus was finally identified. The aim of this work is the introduction of B. cereus as a differential diagnosis of sepsis in patients with acute leukemia in induction chemotherapy, to prevent delayed treatment.

Keywords: Acute leukemia; Bacillus cereus; Fulminant septicemic syndrome.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Anti-Bacterial Agents / therapeutic use
  • Bacillus cereus / isolation & purification*
  • Female
  • Humans
  • Immunocompromised Host
  • Induction Chemotherapy
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy*
  • Sepsis / diagnosis*
  • Sepsis / drug therapy
  • Sepsis / microbiology*
  • Sepsis / mortality

Substances

  • Anti-Bacterial Agents