Nifedipine pretreatment for autonomic dysreflexia during electroejaculation

Urology. 1990 Sep;36(3):228-31. doi: 10.1016/0090-4295(90)80261-k.


Ten spinal-cord-injured males who exhibited autonomic dysreflexia during electroejaculation were given sublingual calcium channel blocker nifedipine pretreatment to prevent this complication. Nifedipine was successful in decreasing peak systolic, diastolic, and mean blood pressures during the procedure. The use of nifedipine resulted in fewer aborted trials and allowed higher energy delivery during the procedure.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Administration, Sublingual
  • Adult
  • Autonomic Nervous System Diseases / etiology
  • Autonomic Nervous System Diseases / physiopathology
  • Autonomic Nervous System Diseases / prevention & control*
  • Blood Pressure / drug effects
  • Drug Evaluation
  • Ejaculation*
  • Electric Stimulation Therapy* / methods
  • Humans
  • Male
  • Nifedipine / administration & dosage
  • Nifedipine / therapeutic use*
  • Reflex, Abnormal / drug effects*
  • Spinal Cord Injuries / complications
  • Spinal Cord Injuries / physiopathology


  • Nifedipine