Refraction in diabetics during metabolic dysregulation, acute or chronic. With special reference to the diabetic myopia concept

Acta Ophthalmol (Copenh). 1990 Jun;68(3):275-80. doi: 10.1111/j.1755-3768.1990.tb01922.x.


The influence of diabetic dysregulation on refraction was analysed by a short-term and a long-term approach. a) Out of 15 patients admitted due to high blood sugars and followed over weeks, 11 showed refractive fluctuation of 1-6.5 D, in either direction-often with excess hypermetropia, while 4 appeared refractively stable. In those with refractive change a transient increase of lens thickness was suggested from ultrasound measurements. b) Diabetes control was evaluated retrospectively in 74 adult diabetics, mainly based on repeated 24 h urine glucose determinations over a 6-year period. As a group, those with low myopia did not score worse than those who had stayed emmetropic. Among the myopes, diabetes duration was longer in the subgroup where diabetes preceded myopia onset. - All considered, we found no support for dysregulation per se as an underlying factor behind the 'diabetic myopia' previously reported from our clinic.

Publication types

  • Comparative Study

MeSH terms

  • Acute Disease
  • Adult
  • Anterior Chamber / physiopathology
  • Blood Glucose / metabolism
  • Chronic Disease
  • Diabetes Mellitus, Type 1 / complications*
  • Diabetes Mellitus, Type 1 / metabolism
  • Female
  • Humans
  • Lens, Crystalline / physiopathology
  • Male
  • Middle Aged
  • Myopia / etiology*
  • Myopia / metabolism
  • Refraction, Ocular
  • Refractive Errors / etiology*
  • Refractive Errors / metabolism
  • Retrospective Studies


  • Blood Glucose