Draft Genome Sequence of Streptomyces rapamycinicus Strain NRRL 5491, the Producer of the Immunosuppressant Rapamycin

Damir Baranasic; Ranko Gacesa; Antonio Starcevic; Jurica Zucko; Marko Blazic; Marinka Horvat; Kresimir Gjuracic; Stefan Fujs; Daslav Hranueli; Gregor Kosec; John Cullum; Hrvoje Petkovic

doi:10.1128/genomeA.00581-13

Draft Genome Sequence of Streptomyces rapamycinicus Strain NRRL 5491, the Producer of the Immunosuppressant Rapamycin

Genome Announc. 2013 Aug 8;1(4):e00581-13. doi: 10.1128/genomeA.00581-13.

Authors

Damir Baranasic¹, Ranko Gacesa, Antonio Starcevic, Jurica Zucko, Marko Blazic, Marinka Horvat, Kresimir Gjuracic, Stefan Fujs, Daslav Hranueli, Gregor Kosec, John Cullum, Hrvoje Petkovic

Affiliation

¹ Acies Bio d.o.o., Ljubljana, Slovenia.

Abstract

Streptomyces rapamycinicus strain NRRL 5491 produces the important drug rapamycin. It has a large genome of 12.7 Mb, of which over 3 Mb consists of 48 secondary metabolite biosynthesis clusters.