Solitary plasmocytoma of the skull

BMJ Case Rep. 2013 Aug 8:2013:bcr2013200379. doi: 10.1136/bcr-2013-200379.


A 63-year-old man presented with a 4-month history of a slowly growing soft mass at his right parieto-occipital region. Neuroradiological examinations revealed an osteolytic extradural tumour of the skull vault. The outer and inner tables of the skull were partially destroyed by the tumour, but the dura was not involved. The tumour and the invaded bone were totally removed and the skull defect was reconstructed using the outer table of the adjacent intact skull. Histopathological examination confirmed plasmocytoma. Laboratory investigations revealed no systemic myelomatosis. It is very important to differentiate solitary plasmocytoma from systemic myelomatosis since their treatment and prognosis are different. Although the prognosis of solitary plasmocytoma is good, regular follow-up examinations are required for any possibility to progress to systemic myelomatosis.

Publication types

  • Case Reports

MeSH terms

  • Bone Neoplasms / diagnosis*
  • Bone Neoplasms / diagnostic imaging
  • Bone Neoplasms / pathology
  • Bone Neoplasms / surgery
  • Diagnosis, Differential
  • Humans
  • Male
  • Middle Aged
  • Multiple Myeloma / diagnosis
  • Plasma Cells / diagnostic imaging
  • Plasma Cells / pathology*
  • Plasmacytoma / diagnosis*
  • Plasmacytoma / diagnostic imaging
  • Plasmacytoma / pathology
  • Plasmacytoma / surgery
  • Prognosis
  • Radiography
  • Skull / diagnostic imaging
  • Skull / pathology*
  • Skull / surgery