Learning and memory in zebrafish larvae

Front Neural Circuits. 2013 Aug 2;7:126. doi: 10.3389/fncir.2013.00126. eCollection 2013.


Larval zebrafish possess several experimental advantages for investigating the molecular and neural bases of learning and memory. Despite this, neuroscientists have only recently begun to use these animals to study memory. However, in a relatively short period of time a number of forms of learning have been described in zebrafish larvae, and significant progress has been made toward their understanding. Here we provide a comprehensive review of this progress; we also describe several promising new experimental technologies currently being used in larval zebrafish that are likely to contribute major insights into the processes that underlie learning and memory.

Keywords: NMDA receptor; habituation; learning; memory; zebrafish.

Publication types

  • Review

MeSH terms

  • Animals
  • Habituation, Psychophysiologic / physiology*
  • Humans
  • Larva
  • Learning / physiology
  • Memory / physiology*
  • Zebrafish