Polyarteritis nodosa in childhood: recognition of early dermatologic signs may prevent morbidity

Pediatr Dermatol. 2014 Jan-Feb;31(1):e6-9. doi: 10.1111/pde.12207. Epub 2013 Aug 13.


Systemic polyarteritis nodosa (PAN) is a vasculitis that affects small to medium-size arteries. Onset in childhood is rare and can cause significant morbidity. Often, cutaneous manifestations can provide early clues toward diagnosis. This article describes a case of childhood systemic PAN that presented with fever, a necrotic skin lesion, and oral ulceration. Intestinal perforation complicated this case. Prompt recognition of childhood PAN is important to prevent serious complications.

Publication types

  • Case Reports

MeSH terms

  • Child, Preschool
  • Colon / pathology
  • Early Diagnosis
  • Humans
  • Immunosuppressive Agents / therapeutic use*
  • Male
  • Morbidity
  • Polyarteritis Nodosa / diagnosis*
  • Polyarteritis Nodosa / drug therapy*
  • Polyarteritis Nodosa / pathology
  • Skin / pathology


  • Immunosuppressive Agents